The annual Highway 61 Yard Sale is underway through Monday, spanning nearly 61 miles from Jackson to Bloomsdale, with drivers urged to use caution. Read More

LINCOLN COUNTY, Mo. - Officials are investigating after the driver of an overturned tractor-trailer was not at the scene following a crash overnight Thursday on Highway 61. According to Missouri State ... Read More

First responders are searching for the driver and any potential passengers of a semi-truck after it rolled over on Highway 61 at John Creech Road in Lincoln County. Read More

State officials issued the following statements on Monday afternoon: Missouri Route 168 in Marion County is NOW OPEN between U.S. Route 61 and Route JJ after being closed to a train derailment. Monday ... Read More

As Wentzville continues to grow, major infrastructure projects - including improvements to Interstate 70, Highway 61, Wentzville Parkway and Route Z - are well underway. These projects are designed to ... Read More

ST. CHARLES COUNTY - State leaders have been working for years on a plan to transform Highway 61 into a six-lane highway through much of St. Charles County. Now, they are ready to make some of those ... Read More

OLD APPLETON, Mo. (KFVS) - The annual Old Appleton Fall Festival is set for Saturday, November 1. Organizers say it will be at the red bridge off of Highway 61 in Old Appleton. They'll have a bounce ... Read More

A woman was killed when her car pulled into the path of an SUV on U.S. Highway 61, troopers say. Read More

A motorcyclist riding south on U.S. Highway 61 was killed when a driver pulled out in front of him Saturday evening in Jefferson County. Read More

A four-vehicle crash on Highway 61 near Old Monroe, Mo. resulted in the death of a 23-year-old woman and three others injured, with the crash occurring when a Hyundai Sonata failed to stop at a stop ... Read More

An officer with the Palmyra Police Department conducted a traffic stop at approximately 10:10 a.m. Thursday, May 1, on southbound U.S. Highway 61 for a lane violation. During the stop, the officer obs ... Read More

JACKSON, Mo. (KFVS) - Starting on Friday, February 7, some drivers in southeast Missouri may find it a little easier to get around. Highway 61 in Jackson will fully reopen after an improvement ... Read More

A rendering of the proposed changes to the I-70 and I-64 / U.S. Route 61 interchange. The long-term project to expand Interstate 70 crossed another ... The project will expand the Missouri's major ... Read More

PIKE COUNTY, Mo. - A man died in a crash Wednesday ... the car crossed the center line past the exit ramp to Highway 61 in Bowling Green. The vehicle began sliding in the snow and went off ... Read More

Two people were injured in a three-vehicle crash in Graves County, Kentucky. A 16-year-old was arrested in connection with a Paducah shooting that left an 18-year-old injured. Emergency crews ... Read More

According to Scott County Central, it happened around 3:25 p.m. on Monday, January 13 at a bus stop on Highway 61 near Morley. Sgt. Clark Parrott with the Missouri State Highway Patrol said the child ... Read More

HANNIBAL - A Missouri Lottery player won $100,000 on a '?20X Crossword'? Scratchers ticket bought at Ayerco, 304 Highway 61 S in Hannibal. The winner explained she and her family were sitting at the ... Read More

Multiple agencies responded to a commercial structure fire report just before 1 p.m. Thursday, Oct. 3 along the 17000 block of US Highway 61 just south of Sikeston in New Madrid County. No one was in ... Read More

Clark Parrott with the Missouri State Highway Patrol said they are on scene assisting the Scott County Sheriff's Department and Scott County Fire with a 22-acre field fire ... Read More

Part of Highway 61 is closed in Scott County, Missouri due to a field fire. According to the City of Benton, Missouri, Highway 61 at the Morley Building Supply in Oran is shut down due to a field fire ... Read More

The sale stretches from Jackson to Festus along Highway 61. Organizers have a list of sales along the route on the Highway 61 Yard Sale Facebook page. Those traveling in the area ... Read More

Kennys Bar N Grill, 7045 US Highway 61 / 67, Barnhart, MO 63012-1533, United States,Barnhart, Missouri View on map ... Read More

Just minutes away from the region's major crossroads of I-70 and U.S. Highway 61 in Wentzville, Missouri, this is an easy afternoon adventure for locals from St. Louis and St. Charles County or ... Read More

HANNIBAL - Weather permitting, beginning July 22, U.S. Route 61 is tentatively scheduled to close from just south of the Iowa State line to east of U.S. Route 136, near ... Read More

According to the Butler County coroner, the man killed was 61-year-old Paul Wilhite of Brinkley, Arkansas. The Missouri State Highway Patrol reported it happened at the Camelot RV Park across from ... Read More

The Perryville Industrial Park is around 400 acres, nestled around Interstate 55, U.S. Route 61 and Missouri Route 51, with easy railroad access. Many of the community's workers have found ... Read More

WENTZVILLE, Mo. - A car chased Sunday morning in Wentzville ends with the suspect in custody. Sunday police pursued a car driving on U.S. Highway 61 in the Wentzville area at around 8:30 a.m., ... Read More

WENTZVILLE, Mo. - A 16-year-old boy was struck and killed in a hit-and-run on Highway 61 in Wentzville Wednesday night. The Missouri State Highway Patrol said he was struck while walking ... Read More