JEFFERSON CITY - Just weeks after a wrong-way crash left two people dead near downtown St. Louis, state transportation officials are installing a special alert system aimed at improving safety. Read More

A Ballwin city employee has been charged with murder in the fatal shooting of a man during an argument Tuesday afternoon on an Interstate 64 exit ramp in O'Fallon, Missouri. Robert R. Farek, 48, of ... Read More

Ray Hartmann, St. Louis journalist and Riverfront Times founder, dies in tragic I-64 car crash involving a semi truck wheel striking his car. Read More

A fatal crash shut down a major roadway in St. Louis County, according to the Missouri State Highway Patrol. Officials told 5 On Your Side that the crash happened in the eastbound lanes of ... Read More

A 73-year-old man from Richmond Heights was killed Thursday afternoon when two tires from a semi truck crashed through the roof of his car on Interstate 64. Read More

ST. LOUIS COUNTY, Mo. - A fatal crash has caused some major backups in the eastbound lanes of Interstate 64 near Interstate 270 on Thursday afternoon. According to the Missouri State Highway Patrol, a ... Read More

Two officers were injured and one person (who is not an officer) was killed in a wrong-way crash Friday afternoon in St. Louis County near I-170 and I-64. Read More

ST. LOUIS - Traffic is slightly resuming following a vehicle fire that happened northbound on I-270, just south of I-64 on Wednesday. According to the Missouri Department of Transportation (MoDOT), a ... Read More

ST. LOUIS, Mo. (First Alert 4) - A semi-truck fire closed lanes of northbound Interstate 270 in St. Louis County. Officials said the vehicle caught fire before 11 a.m. in the northbound lane of ... Read More

A vehicle fire shut down numerous lanes of Interstate 270 in St. Louis County on Wednesday morning. The Missouri Department of Transportation said the incident happened just before 11 a.m. near the ... Read More

B Many people emerged from their cars in the pouring rain. Some came by wheelchair or with strollers to the '?No Kings'? protest at the Tamm Avenue Overpass, which crosses Interstate 64, in St. Louis' ... Read More

A view of westbound Interstate 70, center, at the interchange with Interstate 64 (Hwy 40), left, and U.S. Hwy. 61, right, in Wentzville as seen on Thursday, April 6, 2023. Various plans from the state ... Read More

Crews shut down the westbound lanes of the highway near Timberlake Manor Parkway between Highway 141 and Clarkson Road for several hours. Read More

Multiple lanes are shut down Tuesday morning after reports of a multi-vehicle crash on Interstate 270. The crash took place around 6 a.m. on northbound I-270 before I-64, ... Read More

ADAIR COUNTY, Mo. (First Alert 4) - A Wentzville man and teen were killed and two others were injured Friday afternoon in a crash in Adair County, Missouri. According to the Missouri State Highway ... Read More

The Missouri State Highway Patrol closed northbound Interstate 270 Tuesday afternoon for a fatal crash investigation. Read More

The commute through Town and Country and Chesterfield stands to get a little ... construction on the interchange connecting Interstate 64 and Route 141. The project has been necessitated by ... Read More

A rendering of the proposed changes to the I-70 and I-64 / U.S. Route 61 interchange. The long-term project to expand Interstate 70 crossed another ... The project will expand the Missouri's major ... Read More

St. Charles, MO (February 21, 2025) - A two-vehicle collision on eastbound Interstate 64 early Friday morning resulted in injuries to one driver and significant vehicle damage. According to reports ... Read More

ST. LOUIS - A Weather Impact Alert has been ... The best chance of impactful accumulating snow is along and south of Interstate 70 in Missouri and along and south of Interstate 64 in Illinois. Read More

ST. LOUIS - Road conditions all across Missouri are continuing to improve, continuing giving first responders and snow-clearing crews room to do their jobs safely following the weekend storm that ... Read More

Snowplows are working hard to maintain critical bridge lanes and keep traffic moving on the snow-covered roads of St. Louis, while city officials urge residents to stay home unless travel is ... Read More

It was a morning of helping others. The St. Louis Metropolitan Police used their SUV to push two drivers stuck on the Kingshighway Boulevard exit ramp from eastbound Interstate 64-their mission to ... Read More

Missouri State Highway Patrol helped 379 stranded drivers in the St. Louis area between midnight and 8:00 pm Sunday. Read More

ST. LOUIS - A winter storm pummeled the St ... mainly on the still-hazardous roadways of Interstate 64. The department was in the process of shutting down the on-ramp to I-64 at Chesterfield ... Read More

ST. LOUIS - A powerful ... Counties between the Interstate 70 and Interstate 44 corridors in Missouri, in addition to those south of Interstate 64 in Illinois, are likely to experience sleet ... Read More

Ward 2 includes neighborhoods east of Highway K, south of Highway 364 and north of Interstate 64. In Ward 3 ... developments and the expansion of Lake St. Louis Boulevard. O'Fallon's Ward ... Read More

The Chesterfield, Missouri area is famously known as the "The Gumbo Flats," derived from its soil, and is located approximately 25 miles west of downtown St. Louis along Interstate 64 ... Read More

St. Louis, MO (September 21, 2024) - A serious traffic accident occurred on Saturday morning, September 21, at approximately 8:40 a.m. on Interstate 70, just east of the Missouri 141 exit. The ... Read More

Westbound on Interstate 64 is closed after a crash occurred early Thursday morning. The crash occurred a little after 5 a.m. near Chesterfield Parkway West. Clearance is ... Read More

On Halloween in 2022, police say a man used GPS to track down a family member's stolen car in Sunset Hills, and shot at the suspects on U.S. Highway 40 (Interstate 64). The man and some of the theft ... Read More

One of St. Louis' largest health systems has purchased a vacant warehouse in the Central West End as a new site for ... prominent site on Boyle Avenue by Interstate 64, next to the building ... Read More

LAKE ST. LOUIS, Mo. - A woman died in a St. Charles County crash on I-64 Thursday morning. The Missouri State Highway Patrol has identified the victim as Karen Sweeney, 67, of Foristell. Read More