An Indianapolis-area man and a man from Kansas died Wednesday afternoon in the two-semi crash on Interstate 65 in White County. Read More

LAFAYETTE, Ind. - Multiple agencies responded to a hazardous materials incident that resulted in around 300 gallons of a corrosive liquid leaking from a semi on Thursday night. Crews with the ... Read More

LAFAYETTE, Ind. - Emergency crews responded Thursday night to a hazardous materials spill on South Street in Lafayette, leading to significant traffic delays and road closures near Interstate 65, ... Read More

The truck began leaking the chemical on the 3900 block of south street, close to the Riviera Maya, traveled eastbound to I-65, and proceeded northbound on the interstate. After the leak was detected, ... Read More

Northbound traffic on Interstate 65 remained slow during Wednesday's morning commute several hours after a semi caught fire, according to an Indiana State Police report. Tippecanoe County sheriff's ... Read More

A fatal crash caused the closure of I-65 near Lafayette for multiple hours on Monday. According to the Indiana Department of Transportation, multiple lanes of I-65 ... Read More

A motorcyclist died Monday morning on Interstate 65 after the rider lost control, traveled into the median and struck the cable barrier, police said. Read More

A fatal crash has closed a portion of I-65 near Lafayette. According to the Indiana Department of Transportation, the northbound and southbound lanes are closed near mile marker 164, south of ... Read More

TIPPECANOE COUNTY, Ind. - A reported fatal crash has caused the closure of I-65 near Lafayette. According to the Indiana Department of Transportation, multiple lanes of I-65 northbound and southbound ... Read More

The Indiana State Police Lafayette District conducted multiple targeted enforcement patrols throughout the district over the weekend focusing on aggressive driving, impaired driving, and other traffic ... Read More

LAFAYETTE, IN - A Michigan man led police on a high-speed chase across Interstate 65 Wednesday, allegedly speeding through several counties before being arrested by Indiana State Police. ISP received ... Read More

State troopers are investigating a shooting that occurred on southbound Interstate 65 near 61st Avenue shortly before 2:30 p.m. Monday. Read More

Nighttime lane closures will affect a section of Interstate 65 in Tippecanoe County. Here's what you need to know. Read More

The Indiana State Police officers responded to a medical emergency call around 8 a.m. from a vehicle parked on the shoulder of Interstate 65 south of Lafayette. Read More

A Northwest Indiana man was taken into custody Friday after allegedly driving a motorcycle with no taillights at speeds exceeding 100 mph on Interstate 65 ... traffic stop near Lafayette as ... Read More

The second annual event, hosted by the Junior League of Lafayette, drew large crowds eager to get up close and personal with the vehicles that keep their community running. Read More

:LaFayette Public Safety Director Stacey Meeks confirms that 2 people died in a low-wing plane crash on the runway at theBarwick-LaFayette Airport.EARLIE ... Read More

According to a news release, the Tippecanoe County Coroner's Office responded to an apartment located in the 100 block of Cochise Trail, near Interstate 65 and South Street, in Lafayette, IN after two ... Read More

LAFAYETTE, Ind. - A portion of I-65 northbound is closed because of an accident involving multiple vehicles. According to the Indiana Department of Transportation, I-65 northbound around the 175 mile ... Read More

Luisana Acevedo Sampayo is the woman killed Thursday morning in a one-car, rollover accident on Interstate 65. Read More

LAFAYETTE, Ind. (WISH) - A driver was arrested after he crashed his car and killed a passenger Thursday morning on I-65 southeast of Lafayette, Indiana State Police say. The identity of the ... Read More

A driver was arrested after a fatal crash on I-65 near Lafayette, Indiana, killing a passenger. The driver was preliminarily charged with OWI causing death and neglect of a dependent. Read More

A traffic accident in the northbound lanes of Interstate 65 between the Dayton and Frankfort exits snarled traffic Tuesday morning. Read More

Closures are again planned for Interstate 65 ramps in Franklin. The State Road 44 and I-65 interchange ramps will close one at a time for up to four nights for paving operations, the Indiana ... Read More

SOUTHERN INDIANA - As of 1:15 p.m. Monday, Indiana State Police was advising motorists to avoid Interstate 65 between the Austin and Henryville exits. ISP was working three separate crashes in ... Read More

LAFAYETTE, Ind. (WLFI) -UPDATE: S standoff situation on the north end of the city has ended. We will have more information as it becomes available. Lt. Justin Hartman says a man fled a traffic stop ... Read More

LAFAYETTE, Ind. - Indianapolis Metropolitan police tried to stop a suspect, who fled instead of pulling over, leading police from several agencies on a northbound pursuit on Interstate 65, according ... Read More

LAFAYETTE, Ind. - No one knows yet who the man was walking on Interstate 65 near the Lafayette / Indiana 26 exit or why he was walking on the six-lane highway, but he died after being struck by a ... Read More

Welcome home to Beau Jardin, located in Lafayette, Indiana, just off Highway 52, making it easy to get to Purdue University campus and to Interstate 65. Our community is nestled away to give you the ... Read More

The bridge has been closed since Aug. 7, which has caused lengthy delays for drivers on a 52-mile detour from near Lebanon around the west side of Lafayette and West Lafayette. Read More

WSBT CBS 22 provides news, sports, entertainment and public interest programs to the South Bend, Indiana area including Mishawaka, Notre Dame, Granger, Osceola ... Read More