City says affected area covers North Hills Street, Highway 493 and Poplar Springs Drive ... Read More

A dump truck overturned in Hattiesburg and lost its load. The crash occurred on Highway 49 southbound near Roy Tucker Road on August 26, 2026. According to ... Read More

JACKSON, Miss. (WJTV) - A North Jackson resident has called for action, saying the road leading to her home has been neglected for years. There are multiple potholes, trash and dead trees lining Old ... Read More

Officials in Stone County have closed Highway 49 in Stone County. Read More

JACKSON, Miss. (WJTV) - Earlier this week, WJTV 12 News shared the story of Ashlee Sumrall, 17, who lost her life in a crash on Highway 49 and Cynthia Road in Jackson. Some residents said the ... Read More

Gulfport police are investigating after two people were killed and one was injured during a shooting. The shooting occurred at a Walmart gas station on Highway 49 around 1:30 ... Read More

The Harrison County coroner identified the two people shot dead in a targeted attack outside the Walmart Neighborhood Market in Gulfport off Highway 49. Read More

Officials with the Gulfport Police Department are investigating after a shooting at a Highway 49 gas station on Tuesday. Read More

The Mississippi Highway Patrol is investigating a deadly two-vehicle crash in Simpson County.Troopers responded just after 8 a.m. Monday on Highway 49 North near Cox Road.Investigators said a Dodge ... Read More

Indian Cuisine and Curry Pizza, also known as I-10 Dhaba, opened in Gulfport in September and has become a local favorite around the intersection of Interstate 10 and Highway 49. It's landed a ... Read More

Sheriff Stewart said there were six people in the van at the time of the crash. Read More

COVINGTON COUNTY, Miss. (WHLT) - A Texas woman was killed during a crash in Covington County, according to the Mississippi Highway Patrol (MHP). The crash occurred on U.S. Highway 49 around 5:00 a.m. Read More

Good news for those of you who have been waiting for the new Gulfport Aldi location to open up. Aldi officials confirmed on the chain's website that the Orange Grove store, just off Highway 49, will ... Read More

A Hattiesburg woman was killed during a crash early Thursday morning. The crash occurred on Highway 49 in Forrest County around 4:30 a.m. on November 6, 2025. Read More

Emergency crews are responding to what officials are calling a '?large incident'? at the CF Industries plant on Highway 49, just north of Yazoo City. The Yazoo County Emergency Management Agency ... Read More

A man was killed early Wednesday in a two-vehicle crash at the intersection of Highway 49 North and the Walmart traffic light in Magee ... Read More

FORREST COUNTY, Miss. (WDAM) - Crews are on the scene of a multi-vehicle accident in Forrest County on Highway 49 South. According to a release from the Mississippi Department of Transportation, ... Read More

MAGEE, Miss. (WDAM) - A man from Ellisville was killed in a crash on Highway 49 in Magee on Tuesday morning. Around 3:50 a.m., a crash occurred at the intersection of Highway 49 North and the Walmart ... Read More

The Magee Police Department is investigating a fatal wreck. At about 4 a.m. on Oct. 8, Cory Chancellor, of Ellisville, was killed in a crash at the Walmart traffic light at Highway 49 North in Magee. Read More

Chief Denis J. Borges reminded the public that all suspects are presumed innocent until proven guilty in a court of law. Read More

Chief Denis J. Borges reminded the public that all suspects are presumed innocent until proven guilty in a court of law. Read More

GULFPORT, Miss. (WLOX) - A man was stabbed at a Circle K gas station early Friday morning, Gulfport Police say. GPD says the stabbing happened around 2 a.m. outside the gas station on Highway 49 at ... Read More

A crash closed Highway 49 Thursday morning and seriously injured one person, the Mississippi Highway Patrol said. A car and motorcycle collided on Highway 49 just south of Highway 67. First responders ... Read More

Forrest County deputies are investigating after a woman was injured during a hit-and-run. The incident occurred in Rawls Springs near Highway 49 just before ... Read More

RANKIN CO., Miss. (WLBT) - A woman was taken to a Jackson hospital after she was involved in a crash with an 18-wheeler on Highway 49. According to Florence Fire Chief Richard Wilson, the collision ... Read More

MCHENRY, Miss. (WLOX) - One business in McHenry can be spotted off Highway 49 and stands out due to its vintage cabin look. The history of The Pecan House dates back roughly two decades. Read More

GULFPORT, Miss. (WXXV)- The City of Gulfport issued an extended road closure, impacting citizens and businesses on O'Neal Road. The section of O'Neal Road between Highway 49 and Old Highway 49 will ... Read More

A Jackson man was arrested after a chase from Rankin County almost to Newton County. On April 2, 2025, Richland police said they attempted to stop a motorcycle on Interstate 20 near Highway 49 around ... Read More

The investigation remains ongoing, and further details will be provided as they become available. Read more here. Read More

the Hattiesburg Police Department confirmed. Around 11:45 a.m., officers were dispatched to the railroad tracks near Highway 49 and West Pine Street after receiving reports of a collision ... Read More

One person was injured after two semi-trucks crashed on Highway 49 on Friday morning. According to Dan Beasley with the Seminary Volunteer Fire Department, one person was extricated from a vehicle and ... Read More

Savvy Sliders restaurant held a grand opening for its Gulfport location on Wednesday and people lined up around the building on Highway 49 thirty minutes before it opened. Savvy Sliders has several ... Read More

As for the massive widening project underway on I-10 between Bay St. Louis and Long Beach, you may have noticed a shift in the travel lanes. In 2024, MDOT crews widened the outside shoulder throughout ... Read More

MDOT announced that Highway 49 South ramp to I-10 west will be temporarily closed for maintenance in Harrison County today. The closure is from noon to 4 p.m. for guardrail repair / inspection. Read More

The USDA is to purchase up to $55 million in farm-raised catfish and Gulf shrimp. The Institute for Marine Mammal Studies is continuing to provide treatment for 22 Kemp's ridley sea turtles brought ... Read More

Gulfport Police are investigating a shooting that happened in the 11000 block of Highway 49 on Monday evening. Officers responded to the location about 5:51 p.m. in regard to a report of a shooting. Read More

A deadly crash early Sunday morning claimed the life of a Hattiesburg man, according to the Mississippi Highway Patrol (MHP). The incident happened at approximately 3:00 a.m. on Highway 49 in Forrest ... Read More

One person is dead as a result of a single vehicle accident on Highway 49. Mississippi Highway Patrol said the accident happened about 11 a.m. Wednesday just south of Wiggins. The SUV ended up in the ... Read More

Fresquez, the driver, fled the stop, heading north on Highway 49, recklessly running red lights and ... The Florence Police Department extended gratitude to the Richland Police Department and the ... Read More

The collision happened just after 3 p.m. The vehicle is fully engulfed and first responders are on the scene at Sunflower Road and Highway 49. Firefighters from Sunflower, McHenry and Wiggins are ... Read More

HANCOCK COUNTY - A World War II soldier who died during the Normandy Invasion has had a bridge named after him on the Mississippi Gulf Coast. You'll find the bridge on Highway 49 north of Gulfport. A ... Read More

A Laurel, Mississippi man is dead after a Monday afternoon crash in Stone County. According to the Mississippi Highway Patrol (MHP), 65-year-old Bruce Gavin was killed in the crash. MHP says a 2021 ... Read More

A Laurel man died Monday afternoon in a fatal crash on Highway 49 in Stone County. 65-year-old Bruce Gavin of Laurel was traveling north on Highway 49 when his vehicle left the roadway and collided ... Read More

A wreck with injuries is causing delays on Highway 49 Friday morning. According to the Gulfport Police Department, the wreck happened near Mellenger Street. Northbound and southbound lanes of Highway ... Read More

A Gulfport man who was barreling down Highway 49 in a Ford F-250 truck when he fatally struck ... Gulfport police found the pickup truck hidden under some brush at a Mississippi Coast home. Judge ... Read More

Gulfport working on commercial roads, development The Gulfport Commerce Corridor funding will be used to connect Canal Road to U.S. 49, the city's busiest shopping area. Read More

Former JPD officer wanted for murder captured in Louisiana When deputies attempted to stop the car in Mendenhall, they said the suspects took off on Highway 49. The chase ended in Richland when ... Read More

A Seminary woman died after she was hit by a car while walking on U.S. Highway 49. According to the Mississippi Highway Patrol, the collision happened around 6:30 p.m. on Jan. 28 along U.S. 49 in ... Read More

The crash, occurring on Marion County Highway 49 near Alabama Highway 253, is currently under investigation by state troopers. Read More

Mississippi Highway Patrol is investigating a Saturday night crash in Stone County that left one person dead. MHP responded to the crash at 5:30 p.m. on Highway 49. A Volkswagen driven by 71-year-old ... Read More

At least one person is dead following a serious accident Saturday on Highway 49 near McDaniel's General Merchandise in McHenry. Read More

7-Three current Mississippi Gulf Coast Community College, Perkinston Campus, students who were involved ... in collided with a Dodge Charger early Tuesday morning on Highway 49 in Stone County. The ... Read More

On Tuesday, December 5, 2023, at approximately 2:00 a.m., the Mississippi Highway Patrol responded to a fatal crash on Highway 49 in Stone County. A 2016 Dodge Charger driven by 45-year-old Valerie ... Read More

Officials say an Ocean Springs teen was killed and two other women were injured in an early morning wreck on Tuesday, Dec. 5 on Highway 49 in Stone County.A 2016 Dodge Charger driven by 45-year-old ... Read More

COVINGTON COUNTY, Miss. (WDAM) - First responders are on the scene of a fatal two-vehicle collision on U.S. Highway 49 in Covington County Tuesday. According to Covington County Coroner Chris DaQuila, ... Read More

We have information on a wreck on Highway 49 in Gulfport. News 25's Ansley Brent is on the scene with more on what happened as well as traffic information. Read More

Agents with the Mississippi Bureau of Investigation (MBI) are investigating after one person was killed during a shooting. The shooting happened on Highway 49 in Mt. Olive around 5:30 p.m. on Tuesday, ... Read More

C OVINGTON COUNTY, Miss. (WDAM) - The Mississippi Bureau of Investigation (MBI) is investigating a shooting that occurred on Highway 49 in Covington County around Mount Olive. MBI was notified around ... Read More

The Mississippi Highway Patrol is investigating a crash that killed a Mississippi man Friday afternoon. The incident happened at approximately 2:30 p.m. on Highway 49 Friday. Phillip Skipper, 25, of ... Read More

A portion of US 49 in Gulfport, Mississippi will close while railroad crossing gets replaced. This will cause traffic issues near Interstate 10. Read More

The Mississippi Department of Transportation says Friday that inspectors found damage to the U.S. Highway 49 bridge over Richland Creek in Rankin County. Read More

Related: Failing and forgotten: Black students languish as a Mississippi town reckons with its painful past Today, Yazoo City Municipal School District ... Driving north on US Highway 49 from Jackson, ... Read More

Highway 49 in Gulfport was shut for about 10 minutes Wednesday morning while emergency crews cleaned up a chemical spill. It happened near the intersection of Hwy 49 and O'Neal Road. Read More