Parents, good Samaritans and law enforcement officers lined Highway 45 just before the Artesia Road intersection Tuesday after a Lowndes County School District bus and a vehicle collided, sending ... Read More

The Mississippi Department of Transportation announced updates on several construction and maintenance projects in northeast Mississippi, including mill and overlay on Highway 25 and Highway 45 ... Read More

A military jet crashed Tuesday in a field off Highway 45 near Shuqualak. Read More

Two adults and a teen were killed in a two-car wreck on Highway 45 in Baldwyn Saturday night. The Baldwyn Police Department is still investigating the accident but has said that one car was traveling ... Read More

MONROE COUNTY, Miss. (WCBI) - A Monroe County man has died in a single-vehicle accident. The crash occurred on Wednesday night on Highway 45 Alternate, just north of Highway 41 near Okolona. Monroe ... Read More

Medics airlifted one person to the hospital after a wreck in Guntown. The wreck happened shortly before noon on Highway 45, according to Guntown police. An 18-wheeler and a car collided, and medics ... Read More

A man found naked at a Prentiss County park just off Highway 45 Friday morning has been charged with felony drug possession after deputies found a large quantity of a prescription painkiller in his ... Read More

On Friday afternoon, law enforcement was informed about a crime occurring at the Islamic Center of Mississippi and Alabama, which is located at 4329 Highway 45. It was reported that subjects were ... Read More

One person is dead after a horrific crash in Clay County. The Mississippi Highway Patrol is still investigating the accident. It happened on Highway 45 Alternate, about a mile south of West Point, ... Read More

One person died in a Thursday, May 1 crash in Clay County. The crash happened on Highway 45 Alternate, south of West Point, Clay County Sheriff Eddie Scott said. The Mississippi Highway Patrol is ... Read More

Columbus Police Chief Joseph Daughtry said officers were called to Regions Bank on Highway 45 back on April 9 ... but we owed it to Ms Hollis to do a thorough investigation, and also to the ... Read More

The Mississippi Highway Patrol is investigating the crash. Highway 45 is currently back open. For 24 / 7 news and updates, follow us on Facebook and X. Read More

Noxubee County Coroner, R.L. Calhoun told WCBI that 17-year-old Kennedy Jerome Hopkins, Junior died at the University of Mississippi ... February 1, on Highway 45 near Macon. Read More

The Mississippi Highway Patrol said two cars crashed into one another around 10:43 p.m. on Highway 45 when one crossed the highway in front of the other. Troopers said Johnariya Fandajha Prince, 18, ... Read More

A tragic crash involving two vehicles and road machinery claimed the lives of two people Wednesday evening on Highway 45, the Mississippi Highway Patrol (MHP) confirmed. Read More

Meridian, MS (December 13, 2024) - A tragic accident on Highway 45 claimed the lives of two individuals and left ... options to navigate these difficult times effectively. Contact us today for ... Read More

According to the Mississippi Department of Transportation, the crash happened around 8:12 a.m. on U.S. Highway 45 past Pineville Road. Wayne County Emergency Management says U.S. 45 Northbound lanes ... Read More

(WCBI) - The Mississippi Highway Patrol is investigating ... a Hyundai Genesis travelling South on Highway 45 collided with a piece of mechanical equipment in the road. A Honda Civic also ... Read More

When Clay County Sheriff's Office deputies pulled over a man on Highway 45 South on Wednesday, they found drugs, a firearm and a baby in the car. Read More

TUPELO, Miss. (WTVA) - Tupelo Police responded to a vehicle versus a pedestrian incident on Highway 45. The incident was reported by police around 8:10 p.m. on Wednesday. The incident took place in ... Read More

TUPELO, Miss. (WTVA) - Tupelo Police report a woman was critically injured after being hit on Highway 45. Police posted to X around 8:10 p.m. of a pedestrian versus vehicle south of the Front Street ... Read More

Business leaders and elected officials welcomed a new business to town Wednesday with a ribbon cutting at Pure Home 365. Located at 3119 Highway 45 N. Suite A, across from Mississippi Power, Pure Home ... Read More

(WCBI) - A Winona man died after a two-vehicle crash Monday morning. The Mississippi Highway Patrol responded to a crash around 8:40 a.m. on Highway 45 Alternate in Noxubee County. A 2016 Toyota ... Read More

A Prairie woman was killed in an early morning accident. Monroe County Coroner Alan Gurley said 68-year-old Gwendolyn Blake died at the scene. Read More

The Clarke County Sheriff's Office has confirmed two fatalities during a two-vehicle collision on US 45 / MS 145 at Clarkco State Park.A Dodge 3500 pick-up truck was traveling South on Highway 45, and ... Read More

Taleese Chandler, 20, was shot dead in the early hours Sunday at Club Oasis on Highway 45 Alternate in West Point, Clay County. Read More

A man from Georgia is killed in a Tupelo accident. Lee County Coroner Carolyn Green says the crash happened overnight on Highway 45, near Front Street. 25-year-old Antonio Ramos was walking along the ... Read More

Meridian, MS (October 30, 2023) - A significant accident transpired on Saturday, October 28, at 6:45 p.m. on Highway 45. A 2007 Toyota Sequoia, heading north, collided with a 2015 Ford Explorer ... Read More

MERIDIAN, Miss. (WTOK) - A major car accident occurred on Highway 45 Saturday evening at 6:45pm. A 2007 Toyota Sequoia was travelling north on Highway 45 when a 2015 Ford Explorer attempted to pull ... Read More

TUPELO, Miss. (WTVA) - The intersection of Highway 45 and McCullough Boulevard has one accident per week on average. It's a scary statistic that has convinced the Mississippi Department of ... Read More

The wreck occurred on U.S. Highway 45 south of Scooba. A Mississippi Highway Patrol spokesman, Sgt. Andy West, was on his way to the wreck Wednesday. He said multiple vehicles were involved. Read More

(AP) - A sheriff says a second fatal wreck has occurred this week near a small town in eastern Mississippi ... wreck Wednesday on U.S. Highway 45 south of Scooba. Moore spoke briefly from ... Read More

the accident happened this afternoon on Highway 45 South near Shuqualak on the Kemper-Noxubee county line. Skelding was driving his team of horses on a stretch of road that had little or no ... Read More